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As with any weight-loss agentthe potential exists for abuse of XENICAL in inappropriate patient populationse.gpatients with anorexia nervosa or bulimiaSee INDICATIONS AND USAGE for recommended prescribing guidelines.

Orlistat comes as a capsule and a nonprescription capsule to take by mouthIt is usually taken three times a day with each main meal that contains fatTake orlistat during a meal or up to 1 hour after a mealIf a meal is missed or does not have fatyou may skip your doseFollow the directions on your prescription label or the package label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake orlistat exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor or stated on the package.

Rare cases of increase in transaminases and in alkaline phosphatase and hepatitis that may be serious have been reportedThere have been reports of hepatic failure observed with the use of XENICAL in postmarketing surveillancewith some of these cases resulting in liver transplant or deathsee WARNINGS AND PRECAUTIONSRare cases of hypersensitivity have been reported with the use of XENICALSigns Cheap glucovance patient and symptoms have included pruritusrashurticariaangioedemabronchospasm and anaphylaxisVery rare cases of bullous eruption have been reportedRare cases of leukocytoclastic vasculitis have been reportedClinical signs include palpablepurpuramaculopapular lesionsor bullous eruptionAcute oxalate nephropathy after treatment with XENICAL has been reported in patients with or at risk for renal diseasesee WARNINGS AND PRECAUTIONSPancreatitis has been reported with the use of XENICAL in postmarketing surveillanceNo causal relationship or physiopathological mechanism between pancreatitis and obesity therapy has been definitively establishedLower gastrointestinal bleeding has been reported in patients treated with XENICALMost reports are nonserioussevere or persistent cases should be investigated further.

Taking orlistat can make it harder for your body to absorb certain vitaminsThese vitamins are important if you are nursing a babyDo not use this medicine without a doctor’s advice if you are breast-feeding a baby.

Tell your doctor and pharmacist if you are allergic to orlistat or any other medicationstalk to your doctor if you are taking medications that suppress the immune system such as cyclosporineNeoralSandimmuneIf you are taking cyclosporineNeoralSandimmunetake it 2 hours before or 2 hours after orlistattell your doctor and pharmacist what prescription and nonprescriptionvitaminsnutritional supplementsand herbal products you are taking or plan to takeBe sure to mention any of the followinganticoagulantsblood thinnerssuch as warfarinCoumadinmedications for diabetessuch as glipizideGlucotrolglyburideDiaBetaDynaseMicronasemetforminGlucophageand insulinmedications to control blood pressuremedications for thyroid diseaseand any other medications for weight losstell your doctor if you have if you have had an organ transplant or if you have cholestasiscondition in which the flow of bile from the liver is blockedor malabsorption syndromeproblems absorbing foodYour doctor will probably tell you not to take orlistattell your doctor if you have or have ever had an eating disorder such as anorexia nervosa or bulimiadiabeteskidney stonespancreatitisinflammation or swelling of the pancreasor gallbladder or thyroid diseasetell your doctor if you are pregnantplan to become pregnantor are breast-feedingDo not take orlistat if you are pregnant or breast-feeding.

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